Consistently, Ghsr overexpression further enhanced IRS2 and phosphorylation of CREB and AKT, especially AKT2, under LPS stimulation ( Figures 7 C and S11D ), while IRS1 expression showed no significant difference and p-AKT1 showed a slight trend of increase without statistical significance ( Figure S11D ).
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Nutrient-sensing growth hormone secretagogue receptor in macrophage programming and meta-inflammation.
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