Inhibitor development according to concentrate in severe hemophilia: reporting on 1392 Previously Untreated Patients from Europe and Canada.

Res Pract Thromb Haemost · 2023 · PMC10772871 · PMID 38193044

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a nonsignificant trendno p-value reported

However, these results still contrast with the recent report from the international PedNet registry, showing only a nonsignificant trend of inhibitor development on pdFVIII vs rSHL FVIII (adjusted hazard ratio, 0.90; 95% CI, 0.67-1.21) after adjustment for all known other risk factors for inhibitor development in 1076 PUPs with SHA [ 16 ].

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