Serum lipidomic study of long-chain fatty acids in psoriasis patients prior to and after anti-IL-17A monoclonal antibody treatment by quantitative GC‒MS analysis with in situ extraction.

After receiving anti-IL-17A mAb treatment, there was a decreasing trend in ω-6 PUFAs and a significant increase in ω-3 PUFAs, consistent with MUFAs, with significant differences detected in the second and eighth weeks of treatment (Fig. 3 g).

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