Conversely, dystrophic tibialis anterior muscles exhibited an increasing trend in MCs’ area in Cyanidin+Trametinib than Cyanidin+DMSO control, at the same extent of Trametinib-treated counterparts without Cyanidin supplementation ( Figure 6 B).
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MEK-inhibitors decrease Nfix in muscular dystrophy but induce unexpected calcifications, partially rescued with Cyanidin diet.
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The sentences
In addition, Trametinib-treated muscles displayed a decreasing trend of the Nfix protein, although not statistically significant.