Transcriptomic analysis of sorted lung cells revealed a proviral activity of the NF-κB pathway toward SARS-CoV-2.

Among the top upregulated coding genes in S + cells, we confirmed candidates revealed by previous analyses performed in non-sorted non-vRNA-depleted A549-ACE2 cells, such as CXCL8, CCL20, IL6, and NFKB1, 17 , 36 , 37 but also novel highly significant candidates, including IL32 and ITGAM ( Table S1 ).

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