A population modification gene drive targeting both Saglin and Lipophorin impairs Plasmodium transmission in Anopheles mosquitoes.

Elife · 2023 · PMC10786457 · PMID 38051195

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highly significantno p-value reported

Reviewer #3 (Significance (Required)): This is potentially a highly significant study that could provide a vital mechanism for generating efficient gene drives.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

A population modification gene drive targeting both &lt;i&gt;Saglin&lt;/i&gt; and &lt;i&gt;Lipophorin&lt;/i&gt; impairs &lt;i&gt;Plasmodium&lt;/i&gt; transmission in &lt;i&gt;Anopheles&lt;/i&gt; mosquitoes.

The sentences

A population modification gene drive targeting both <i>Saglin</i> and <i>Lipophorin</i> impairs <i>Plasmodium</i> transmission in <i>Anopheles</i> mosquitoes.