Barely Significant
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Heterogeneity in cardiorenal protection by Sodium glucose cotransporter 2 inhibitors in heart failure across the ejection fraction strata: Systematic review and meta-analysis.

World J Nephrol · 2023 · PMC10789083 · PMID 38230296

Europe PMCDOI
1
hedged sentence
0.0700
closest p · 1.4× alpha
0.0700
boldest claim

The sentences

borderline significanceP = 0.07so close (0.05 < p ≤ 0.1)
Similar to the results of primary outcome analyses, meta-analysis of the composite outcome of ‘cardiovascular death or hospitalizations (or urgent visits) due to heart failure’ exhibited significant improvement in response to treatment with SGLT2i at all the LVEF levels though again, compared to patients with LVEF above 30%, the subgroup of patients with the baseline LVEF of 30% or less showed a stronger response to gliflozins at borderline significance (HR: 0.69, 95%CI: 0.61 to 0.76 vs 0.78, 95%CI: 0.71 to 0.85; P = 0.07).

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