Treatment of HCV with direct-acting antivirals on reducing mortality related to extrahepatic manifestations: a large population-based study in British Columbia, Canada.

An analysis based on US Census and the National Center for Health Statistics reported a decreasing trend of liver-related mortality among patients with HCV infection during the DAA era (2007–2017), while an increasing trend of mortality from cardiovascular disease or diabetes were seen among patients with HCV infection. 40 The authors suggested that the improved longevity in individuals with HCV due to highly effective DAA treatment might be marred by increasing extrahepatic mortality.

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