Mass Spectroscopy Imaging (MSI) revealed a notable trend for adenosine, inosine and xanthine suppression in CT26 tumors from mice treated with anti-CD73 ( Figure 3c and Supplementary Figure S4B).
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Efficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor models.
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