One thousand patients with essential thrombocythemia: the Mayo Clinic experience.

Furthermore, on univariate analysis, age ≥60 years ( p < 0.01), leukocyte count >11 × 10 9 /l ( p < 0.01), presence of cardiovascular risk factors ( p < 0.01), and history of major hemorrhage ( p = 0.01) predicted future hemorrhage, while aspirin use was of borderline significance ( p = 0.10).

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