Although the frequency of Lin – ‐Sca1 + ‐c‐Kit + (LSK) cells was slightly above normal, that of Abin1 Q478H/Q478H Lin – and Lin – ‐c‐Kit + (LK) cells was significantly decreased (Figure 3g ), and the frequencies of megakaryocyte‐erythrocyte progenitors (MEPs), granulocyte‐macrophage progenitors (GMPs), and common myeloid progenitors (CMPs) also showed a decreasing trend compared with those of the WT mice (Figure S2b , Supporting Information).
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ABIN1 (Q478) is Required to Prevent Hematopoietic Deficiencies through Regulating Type I IFNs Expression.
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