One year of treatment with elexacaftor/tezacaftor/ivacaftor in patients with cystic fibrosis homozygous for the F508del mutation causes a significant increase in liver biochemical indexes.

Front Mol Biosci · 2023 · PMC10800484 · PMID 38259684

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an increasing trendno p-value reported

FEV 1 showed an increasing trend after 1 year of treatment with LI and remained stable after 3 years of treatment.

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