Barely Significant
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The relationship between APOE genotype, CSF Tau and cognition across the Alzheimer's disease spectrum, moderation and mediation role of insula network connectivity.

CNS Neurosci Ther · 2024 · PMC10805399 · PMID 37577852

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an increasing trendno p-value reported
As the disease progressed, there was a gradually declining trend in MMSE, RAVLT‐I, RAVLT‐L and CSF Aβ and an increasing trend in ADAS‐cog, CSF Tau and CSF pTau.

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