Toxicological evaluation of a pumpkin-derived pectin preparation: in vitro genotoxicity studies and a 13-week oral toxicity study in Sprague-Dawley rats.

For example, in male rats of the 18,000 ppm G3P-01 group, there was a significant ( P < 0.05) reduction in serum cholesterol level, as well as a highly significant ( P < 0.01) reduction in cholesterol level in the 36,000 ppm G3P-01 group in comparison with the control group ( Table 5 ).

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