Age-related secretion of grancalcin by macrophages induces skeletal stem/progenitor cell senescence during fracture healing.

Bone Res · 2024 · PMC10808101 · PMID 38267422

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Consistent with previous results, the key senescence genes Cdkn2a , Cdkn2c , and Cdkn2d and the “SenMayo” gene set displayed highly significant enrichment in rGCA-treated SSPCs (Fig. 3e, f ).

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