Cell-free chromatin particles released from dying cancer cells activate immune checkpoints in human lymphocytes: implications for cancer therapy.

Front Immunol · 2023 · PMC10808321 · PMID 38274821

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highly significantno p-value reported

We found a highly significant reduction in expression of all three immune checkpoints examined, namely, PD-1, CTLA-4 and LAG-3 ( Figures 4B, C ; Supplementary Figure 4 ).

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