The Therapeutic Potential of Two Egyptian Plant Extracts for Mitigating Dexamethasone-Induced Osteoporosis in Rats: Nrf2/HO-1 and RANK/RANKL/OPG Signals.

Antioxidants (Basel) · 2024 · PMC10812806 · PMID 38247490

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Administration of ACE and EPE to Dex group showed a highly significant ( p < 0.05) decrease in ALP, ACP, IL-6, TNF-α, and RAKNL levels associated with a marked significant ( p < 0.05) increase in OPG and OCN levels along with OPG/RANKL ratio compared to the untreated Dex group.

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