Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease.

On the other hand, the DEP signatures in 5xFAD-DUSP4vs5xFAD in the male mice have marginally significant overlap with the human male DEP signatures in the opposite directions ( Supplementary Figure S9A ), while the signatures from the female mice do not significantly overlap the respective human signatures ( Supplementary Figure S9B ).

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