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An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma.

Oncoimmunology · 2021 · PMC10813564 · PMID 38283034

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a decreasing trendno p-value reported
38 On the other hand, we observed a decreasing trend in the number of Tregs, which could indicate an immune modulatory effect of the vaccine.

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