Heart Failure with Preserved Ejection Fraction: The Pathophysiological Mechanisms behind the Clinical Phenotypes and the Therapeutic Approach.

The authors of the study concluded that during three decades of follow-up, there was an increasing trend in the proportion of HFpEF (defined as LVEF ≥ 50%), from 41% in the period 1985–1994 to 56% in the period 2005–2014 [ 25 ].

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