Long-Term SARS-CoV-2-Specific Humoral and T Cell Responses after the BNT162b2 or BBIBP-CorV Booster and the Incidence of Breakthrough Infections among Healthcare Workers.

During follow-up, a decreasing trend was observed in the first cohort: the median anti-S IgA antibody level significantly decreased from 13.5 S/CO to 10.6 S/CO after six months ( p = 0.021), then slightly decreased to a median value of 9.2 S/CO after twelve months ( p = 0.960).

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In contrast, a slightly increasing trend was observed in the second cohort (5 S/CO, 9.5 S/CO, 9.7 S/CO), but the alterations among the three monitoring time points were not statistically significant. 4.

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In contrast, an increasing trend was observed within the second cohort (85.8%, 98.7%, and 98.4%, respectively).

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