Moreover, we observed an elevated trend in the concentrations of IFN-α and IFN-β in the plasma of patients with NSCLC who underwent cryoablation, especially at day 1 after cryoablation ( figure 5F and online supplemental figure S1I,J ).
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Cryoablation triggers type I interferon-dependent antitumor immunity and potentiates immunotherapy efficacy in lung cancer.
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