Studies have shown that alcohol causes a significant increase in Veillonellaceae and a decreasing trend in Bacteroidaceae and Porphyromonadaceae ( 47 ). 16S rRNA gene sequencing revealed that Peptostreptococcacae , Proteobacteria , Pasteurellaceae and Bacillales were significantly increased, while Lachnospiraceae , Ruminococcaeae , Clostridiales cluster XIV , Prevotellaceae and Bacteroidaceae significantly decreased in ARLC patients ( 48 ).
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