arterial hypertension, heart failure, CAD, and PAD) were all associated with COPD, whilst BMI showed a J-shaped relationship; (iii) COPD was associated with higher use of OAC as well as marginally significant higher OAC discontinuation and an overall differential drug management of AF; (iv) patients reported as having COPD had a worse prognosis at multiple-adjusted Cox regression, including higher risk of all-cause death, MACE, and major bleeding.
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Impact of chronic obstructive pulmonary disease in patients with atrial fibrillation: an analysis from the GLORIA-AF registry.
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Chronic obstructive pulmonary disease was associated with lower odds of treatment with beta-blockers [aOR: 0.79 (0.72–0.87), Figure 2 ], as well as amiodarone and propafenone; we also observed marginally statistically significant lower odds of having received AF ablation or electrical cardioversion [aOR (95% CI): 0.88 (0.78–0.99)].