Effect of computerized cognitive training on mood, cognition, and serum brain-derived neurotrophic factor level in late-life depression - a pilot randomized controlled trial.

Front Psychiatry · 2023 · PMC10827875 · PMID 38298930

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a decreasing trendp = 0.02actually significant

BDNF outcome Changes in serum BDNF level were significantly different between the two groups ( Table 2 ), with the experimental group showing an improving trend and the control group having a decreasing trend over 6 weeks (experimental vs. control = 2088.3 pg/mL vs. -3277.4 pg/mL; group difference = 5365.6 [95% CI = 813.5–9917.8] pg/ml; p = 0.02).

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