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The glycoimmune checkpoint receptor Siglec-7 interacts with T-cell ligands and regulates T-cell activation.

J Biol Chem · 2024 · PMC10831161 · PMID 38141764

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highly significantno p-value reported
The identification of analogous “glycoimmune” T-cell checkpoints may thus be highly significant for the design and development of novel immunotherapies ( 2 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.