These structural alignments with DNAAF3 orthologs have rmsds of ~2.4 to 3.5 Å covering ~140 or more residues with z scores in many cases >10; a score of z = 6 is generally considered highly significant, while a score of z ≤ 2 is meaningless ( Fig. 2 A – C ).
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Methylation of ciliary dynein motors involves the essential cytosolic assembly factor DNAAF3/PF22.
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