Gram negative bacteria related urinary tract infections: spectrum of antimicrobial resistance over 9 years in a University tertiary referral Hospital.

A positive trend, with a significant decrease in the percentage of AMR was found towards Pivmecillinam (decrease: −142.92%; p < 0.001), Ciprofloxacin (decrease: −31.30%; p < 0.001), Trimethoprim (decrease: −25.62%; p < 0.001), Gentamycin (decrease: −19.58%; p < 0.001), Ampicillin/Amoxicillin (decrease: −12.43%; p < 0.001).

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According to our results, the ‘golden antibiotics’ with a decreasing trend of resistance and an adequate overall percentage of efficacy towards GNB are Ciprofloxacin, Fosfomycin, Gentamycin and Pivmecillinam.

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Piperacillin/Tazobactam shows an increasing trend of resistance, with a high mean level of GNB-related resistance.

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