Moreover, Zer treatment enhanced the expression of HMOX-1 and srxn1 in M2 macrophages, which might be significant in reducing proinflammatory M1-like function and contributing to the anti-inflammatory effect of Zer.
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Zerumbone reduces TLR2 stimulation-induced M1 macrophage polarization pattern via upregulation of Nrf-2 expression in murine macrophages.
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