Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans.

Furthermore, a similar association pattern was observed in SNPs near the MIR4458HG gene (distance ~33 kb) in chromosome 5 with marginal significance ( P -value < 1.0E−05) in all models (Table 2 , Additional File 1 : Table S1).

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Note that there were only two SNPs rs116683655 and rs76250200 within gene ISPD with P -value < 1.0E−04 in SIREN were marginally significant with P -values 3.98E−03 and 5.57E−03 in COMPASS, respectively.

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