Barely Significant
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Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria.

Cell · 2023 · PMC10841658 · PMID 37875108

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hedged sentence
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closest p · 0.0× alpha
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The sentences

highly significantp = 0.00013actually significant
The enrichment of these MCTS1 pLOF variants in our male MSMD cohort without genetic diagnosis ( n = 422, 5 pLOF variants) relative to a cohort comprising both male patients without mycobacterial infections and healthy male individuals ( n = 1,932, 0 pLOF variants) was highly significant ( p = 0.00013).

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