Repeated Levosimendan Infusions in the Management of Advanced Heart Failure: Review of the Evidence and Meta-analysis of the Effect on Mortality.

Among secondary end points, there was a marked and highly significant reduction in the rate of HF hospitalization among patients treated with levosimendan (hazard ratio [HR] 0.25; 95% CI, 0.11–0.56; P = 0.001 vs. placebo).

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