In the unadjusted comparison, the TCI provided a highly significant risk stratification for d100, d180 and 2-year NRM, with the cumulative incidences being 4.5% (95% CI, 3.7–5.5), 8.2% (95% CI, 7–9.6) and 16.5% (95% CI, 14.7–18.5) in the low TCI group, rising to 7.3% (95% CI, 6.2–8.5), 11.6% (95% CI, 10.1–13.1) and 21.4% (95% CI, 19.4–23.5) in the intermediate TCI group, and further increasing to 12.4% (95% CI, 8.1–17.8), 17% (95% CI, 11.8–23.1) and 23.5% (95% CI, 17.2–30.5) in the high TCI group, respectively ( p < 0.0001 for all comparisons) (Table 2 ).
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Validation of the transplant conditioning intensity (TCI) index for allogeneic hematopoietic cell transplantation.
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