Corresponding ctDNA and tumor burden dynamics in metastatic melanoma patients on systemic treatment.

Consistent with previous studies, our data also demonstrates a positive trend of increasing plasma ctDNA with increasing total tumor burden both in terms of absolute copies/mL and % VAF ( r = 0.45 to 0.47, p < 0.001, R 2 = 0.31 to 0.50, p < 0.001).

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