Experimental and clinical evidence in favour of an effective immune stimulation in ER-positive, endocrine-dependent metastatic breast cancer.

Front Immunol · 2023 · PMC10850262 · PMID 38332913

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highly significantno p-value reported

This likely allowed the beta IFN-IL-2 sequence to significantly boost the effector immune cells of the innate and adaptive immune response ( Figures 1C , 2 ) as demonstrated by the highly significant increase in total lymphocytes, CD8+, CD4+ T cells and NK cells reported during the clinical benefit of the studied breast cancer patients ( 115 , 117 ).

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