Significantly Improved Cold Preservation of Rat Hind Limb Vascularized Composite Allografts Using the New PrC-210 Free Radical Scavenger.

It is, therefore, highly significant that PrC-210 suppressed, to background, both (i) cytochrome C release in intact rat limbs stored at 4 °C for 48 h ( Figure 3 A, p = N.S.) and (ii) cytochrome C release from rat muscle mitochondria in vitro ( Figure 2 C) that were exposed to a direct ROS insult.

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