Association of Three Genetic Loci with Molar Incisor Hypomineralization in Polish Children.

A lack of an association between each SNP and MIH was found in analyses performed for frequency distributions of major homozygotes, heterozygotes, and minor homozygotes (except for the rs4811117 polymorphism, for which the p -value reached marginal significance at p = 0.017, which is on the borderline if the Bonferroni-corrected significance level of p = 0.05/3 = 0.017 is used for the global chi-squared test with the further tests treated as post-hoc tests).

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Conclusion: Our replication study did not confirm highly significant associations between the single nucleotide polymorphisms rs2889956, rs4811117, and rs13058467 with molar incisor hypomineralization in Polish children. genetic polymorphism molar incisor hypomineralization replication study Program of Polish Minister of Science and Higher Education “Regional Initia

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