Barely Significant
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Vitamin D Supplementation: A Review of the Evidence Arguing for a Daily Dose of 2000 International Units (50 µg) of Vitamin D for Adults in the General Population.

Nutrients · 2024 · PMC10857599 · PMID 38337676

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highly significantp < 0.001actually significant
For example, after two years of supplementing 2000 IU (50 μg) of vitamin D per day in the VITAL trial, the multivariable-adjusted mean serum 25(OH)D concentrations in individuals with a body mass index of <25.0, 25.0–29.9, 30.0–34.9, and ≥35.0 kg/m2 were 110, 103, 98, and 92 nmol/L (44.0, 41.2, 39.4 and 37.0 ng/mL), respectively, indicating a highly significant treatment effect interaction by body mass index ( p < 0.001) [ 93 ].

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