ATG16L1 rs2241880/T300A increases susceptibility to perianal Crohn's disease: An updated meta-analysis on inflammatory bowel disease risk and clinical outcomes.

Overall, OR P was determined to be a highly significant 0.74 (0.72–0.77; p ‐value: <0.001) under the random effects model, indicating that the A allele is favourable against CD development (Figure 2a ).

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