SERPINC1 c.1247dupC: a novel SERPINC1 gene mutation associated with familial thrombosis results in a secretion defect and quantitative antithrombin deficiency.

Comparison of AT-GFP and AT fs -GFP in the cell culture supernatants showed a clear reduction in secretion of AT fs -GFP with a highly significant difference ( p < 0.01) between all AT fs -GFP cell lines and each AT-GFP line (Fig. 3 B).

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