Effective protective agents against the organ toxicity of T-2 toxin and corresponding detoxification mechanisms: A narrative review.

Therefore, MAPK , NF-kappaB, Nrf2, HO-1, p53 , and HMGB1 may be significant targets of T-2 neurotoxicity. 2.4 Protective agent for reproductive toxicity 2.4.1 Protective agents L-Arg (0.25, 0.5, and 1.0 mmol/L) pretreatment upregulated activities of GSH-Px, SOD and CAT in T-2 (10 nmol/L)-treated mouse Leydig cells, thereby alleviating T-2-induced oxidative damage ( Yang et al., 2018 ).

also in 13,097 other papers