GDF15 is a dynamic biomarker of the integrated stress response in the central nervous system.

CNS Neurosci Ther · 2024 · PMC10867791 · PMID 38357857

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highly significantno p-value reported

The highly significant ISR‐related elevation of GDF15 in VWMD is restricted to the CSF and surprisingly not manifested in plasma. 2.

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