In Vitro Hemoglobin Binding and Molecular Docking of Synthesized Chitosan-Based Drug-Carrying Nanocomposite for Ciprofloxacin-HCl Drug Delivery System.

Consequently, the investigation of transport processes in ciprofloxacin–protein system is highly significant in the pharmacological field. 10 , 11 The hydrophobic interaction of nonionic surfactants with proteins has been considered as one of the key factors for preventing aggregation and the agitation-induced denaturation of proteins during biotechnological processes. 12 Hemoglobin molecules can also act as binders for drugs.

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