Lipidomics Analysis Deepen Understanding the Molecular Mechanisms in a Gouty Model Induced by Combination of MSU Crystals Injection and High-Fat Diet Feeding and the Intervention Mechanisms of Allopurinol.

As anticipated, there was an increasing trend of total Car amount (p < 0.005) in model, contributing to elevating the total level from 748.8 ± 48.19 nmol/mL serum in control to 1205 ± 74.28 nmol/mL serum in model, with an ~61 mol% increase in serum ( Figure 5A ).

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