Therapeutic effects and underlying mechanism of poly (L-glutamic acid)-<i>g</i>-methoxy poly (ethylene glycol)/combretastatin A4/BLZ945 nanoparticles on Renca renal carcinoma.

Significance levels were defined as follows: * p < 0.05 (considered statistically significant), ** p < 0.01 (highly significant), *** p < 0.001 (extremely significant), and **** p < 0.0001 (incredibly significant), “ns” indicates that there was no statistically significant difference. 3 Results and discussion Formula optimization and in vivo study of poly (L-glutamic acid)- g -methoxy poly (ethylene glycol)/combretastatin A4/BLZ945 nanoparticles for cancer therapy has been completed as described in one of our previous studies ( Huang et al., 2023 ).

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