Hepatobiliary organoids differentiated from hiPSCs relieve cholestasis-induced liver fibrosis in nonhuman primates.

Given that compensatory bile duct dilatation is expected to take place in the later stages of the bile duct ligation model, abdominal ultrasound examination results in monkeys revealed that the inner diameters of the common bile duct and left hepatic duct showed a decreasing trend compared with the model group at 8 weeks after HBO transplantation, which represents the mending effect of HBOs on the liver and bile duct from the side.

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