Co-crystal of Tramadol-Celecoxib Versus Tramadol or Placebo for Acute Moderate-to-Severe Pain After Oral Surgery: Randomized, Double-Blind, Phase 3 Trial (STARDOM1).

Adv Ther · 2024 · PMC10879371 · PMID 38183526

Europe PMC DOI

hedged sentence

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

failed to reach significanceP = 0.059so close (0.05 < p ≤ 0.1)

CTC 100 mg ( P = 0.013) and CTC 200 mg ( P = 0.003) demonstrated superiority versus tramadol, while the difference between CTC 150 mg and tramadol narrowly failed to reach significance ( P = 0.059).

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