Resistance of HNSCC cell models to pan-FGFR inhibition depends on the EMT phenotype associating with clinical outcome.

Mol Cancer · 2024 · PMC10880239 · PMID 38378518

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highly significantno p-value reported

We found that FGFRi mediated a highly significant downregulation of FGFR signaling in the sensitive UT-SCC 33 and an enhanced FGFR signaling in the resistant UM-SCC 10a cells (Fig. 4 E).

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