Interestingly, we detected a strong tendency towards statistical significance ( p = 0.051) regarding the correlation with circKEAP1 expression and CD8 + T-cell density (Figure S8 B).
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A tumor suppressor protein encoded by circKEAP1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti-tumor immunity.
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