DUX4-r exerts a neomorphic activity that depends on GTF2I in acute lymphoblastic leukemia.

Sci Adv · 2023 · PMC10881058 · PMID 37713484

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highly significantno p-value reported

Using the publicly available datasets ( 6 , 8 ), we found a highly significant overlap of the DUX4-r B-ALL patient gene signature with our DUX4-IGH or DUX4-del50 datasets, which was instead negligent with our wt DUX4 dataset ( Fig. 1B ).

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